Tuesday 25 March 2014

Human Genome Project (HGP

                           HUMAN GENOME PROJECT (HGP)

What is HPG ?


The Human Genome Project (HGP) was the international, collaborative research program whose goal was the complete mapping and understanding of all the genes of human beings. All our genes together are known as our "genome."




The hereditary material, deoxyribonucleic acid (DNA), which contains al of our genes. DNA are made up of 4 nucleic acids guanine, adenine, cytosine and thymine. All genes are made up of stretches of these four bases, arranged in different ways and in different lengths. HGP researchers have deciphered the human genome in three major ways:
  1. determining the order, or "sequence," of all the bases in our genome's DNA
  2. making maps that show the locations of genes for major sections of all our chromosomes
  3. producing what are called linkage maps, complex versions of the type originated in early Drosophila research, through which inherited traits (such as those for genetic disease) can be tracked over generations. 
HGP has given the world a resource of detailed information about the structure, organization and function of the complete set of human genes. This information can be thought of as the basic set of inheritable "instructions" for the development and function of a human being.

HISTORY 
The project began with the culmination of several years of work supported by the US Department of Energy. The ultimate goal of this initiative is to understand the human genome and knowledge of the human is as necessary to the continuing progress of medicine and other health sciences as knowledge of human anatomy has been for the present state of medicine. The proposal was made by Dr. Alvin Trivelpiece and was approved by Deputy Secretary William Flynn Martin.James D. Watson was head of the National Center for Human Genome Research at the National Institutes of Health in the United States starting from 1988.

  ADVANTAGE IN PHARMACY
  Medicine will be help to improve diagnosis of diseases, early detection of genetic diseases and gene therapy. Genetic has also the potential to reveal the differences between the individuals so that suitable treatment can be prescribed and national drug design can be undertaken. Thus treatment can be more focused and effective based on individual requirement.Personal dosage will possible for different type of individual. Thus we can provide effective therapeutic without worried on toxicity development. Study in microbial genomics can develop vaccines, antibiotics, and diagnostics for infectious diseases.

IN FUTURE 
Each person will have their own genome maps. They will be some important document related to our healthy. They might possibility that our carer will be choose from our map. Maybe those genome will help in knowing ourself in chracteristic and personality. Still future contain high possibility and maybe our genome are sell in market.

 SELLING MAP
 TO UNDERSTAND SOMEONE OR OURSELF

Useful website for Pharmacy

National Pharmaceutical Control Bureau (BPFK)

http://portal.bpfk.gov.my/images/top-search-eng.png



The National Pharmaceutical Control Bureau (NPCB), formerly known as the National Pharmaceutical Control Laboratory, was set up in October 1978 under the quality control activity of Pharmacy and Supply Programme. This institution was established to implement quality control on pharmaceutical products. The infrastructure and facilities were designed to meet the requirements for testing and quality control activities - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=4#sthash.Rg8xGewE.dpuf
The National Pharmaceutical Control Bureau (NPCB), formerly known as the National Pharmaceutical Control Laboratory, was set up in October 1978 under the quality control activity of Pharmacy and Supply Programme. This institution was established to implement quality control on pharmaceutical products. The infrastructure and facilities were designed to meet the requirements for testing and quality control activities. - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=4#sthash.JCG4tBiB.dpuf
 The National Pharmaceutical Control Bureau (NPCB) was set up in October 1978 under the quality activity of Pharmacy and Supply Programme. This institution was established to implement quality control on pharmaceutical products. NPCB is a government agency in Malaysia that regulates pharmaceutical, natural (traditional) and cosmetic products. The NPCB is responsible for ensuring the quality, efficacy and safety of pharmaceutical products, as well as the quality and safety of natural (traditional) products and cosmetics marketed in the country.

In this website  we can check whether the product is registered under NPCB. This can be done  by clicking the "Quest" button and in the website and all you need is to key in the registration number of the product or put in the name of the product and BAAAMMM!!! all the info that you need to know will pop up.

You can also find all the information about the drug exactly like in the leaflet. These leaflets are targeted for the consumer, containing the information on how to take the drug works, how to use it, what precautions to take, use of the drug in pregnancy, what to do if you miss a dose, and any possible side effects or interactions.


Consumer Medication Information Leaflets / Risalah Maklumat Ubat untuk Pengguna (RiMUP) are available for prescription and non-prescription medicines registered for use in Malaysia. These leaflets are targeted for the consumer, containing information on how the drug works, how to use it, what precautions to take, use of the drug in pregnancy, what to do if you miss a dose, and possible side effects or interactions. The leaflets are available in English and Bahasa Malaysia. You may download the leaflet and print it out for future reference. Please contact your doctor or pharmacist if you have any further questions about your medicine. You may also call the National Pharmacy Call Center toll-free line at 1800-88-6722 (24-hour service). - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=95#sthash.JTMlFujM.dpuf
Consumer Medication Information Leaflets / Risalah Maklumat Ubat untuk Pengguna (RiMUP) are available for prescription and non-prescription medicines registered for use in Malaysia. These leaflets are targeted for the consumer, containing information on how the drug works, how to use it, what precautions to take, use of the drug in pregnancy, what to do if you miss a dose, and possible side effects or interactions. The leaflets are available in English and Bahasa Malaysia. You may download the leaflet and print it out for future reference. Please contact your doctor or pharmacist if you have any further questions about your medicine. You may also call the National Pharmacy Call Center toll-free line at 1800-88-6722 (24-hour service). - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=95#sthash.JTMlFujM.dpuf
Consumer Medication Information Leaflets / Risalah Maklumat Ubat untuk Pengguna (RiMUP) are available for prescription and non-prescription medicines registered for use in Malaysia. These leaflets are targeted for the consumer, containing information on how the drug works, how to use it, what precautions to take, use of the drug in pregnancy, what to do if you miss a dose, and possible side effects or interactions. The leaflets are available in English and Bahasa Malaysia. You may download the leaflet and print it out for future reference. Please contact your doctor or pharmacist if you have any further questions about your medicine. You may also call the National Pharmacy Call Center toll-free line at 1800-88-6722 (24-hour service). - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=95#sthash.JTMlFujM.dpuf
Consumer Medication Information Leaflets / Risalah Maklumat Ubat untuk Pengguna (RiMUP) are available for prescription and non-prescription medicines registered for use in Malaysia. These leaflets are targeted for the consumer, containing information on how the drug works, how to use it, what precautions to take, use of the drug in pregnancy, what to do if you miss a dose, and possible side effects or interactions. The leaflets are available in English and Bahasa Malaysia. You may download the leaflet and print it out for future reference. Please contact your doctor or pharmacist if you have any further questions about your medicine. You may also call the National Pharmacy Call Center toll-free line at 1800-88-6722 (24-hour service). - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=95#sthash.JTMlFujM.dpuf dissemination to the public, industries, other government agencies as well as 
Drugs.com






Drugs.com is the most popular, comprehensive and up-to-date source of drug information online. Providing free, peer-reviewed, accurate and independent data on more than 24,000 prescription drugs, over-the-counter medicines & natural products from all over the world.

Drugs.com provides access to healthcare information tailored for a professional audience - sourced solely from the most trusted, well-respected and independent agents such as the American Society of Health-System Pharmacists (ASHP), FDA, Micromedex, Harvard Health, Wolters Kluwer Health, Cerner Multum and Stedman's.
You can just add your medications to instantly assemble relevant medical information in a simple, easy to read personalized format. Gain immediate access to in-depth consumer information, drug comparisons, historical news, FDA alerts, drug interactions, plus food, allergy and medical condition interactions.Choose to be notified when new FDA alerts are issued and when any new drugs become available for any of your existing medical conditions. Use Med notes to print wallet size records and manage medications for any number of people.

 You can also download their apps via Android or App Store.






The National Pharmaceutical Control Bureau (NPCB), formerly known as the National Pharmaceutical Control Laboratory, was set up in October 1978 under the quality control activity of Pharmacy and Supply Programme. This institution was established to implement quality control on pharmaceutical products. The infrastructure and facilities were designed to meet the requirements for testing and quality control activities. - See more at: http://portal.bpfk.gov.my/index.cfm?&menuid=4#sthash.JCG4tBiB.dpuf

Monday 3 March 2014

Profile + Protein Info


Description


Assalamualaikum and hello to all followers out there.WHATS UPP!!!! This blog is created with intention to share all of you our thoughts and point of views during our students' life. We are MSU student pursuing our degree in pharmacy (Bachelor of Pharmacy). We also highly encourage your participant in giving us your feedback. Till then .....








Le profile

Haziq Zick

Name: Mohamad Haziq Bin Mohd Yusoff
Age : 23 years old
D.O.B: 10th Feb 1991
From: Johor Bahru, Johor
Specialize: Editing. Photography. 
Hobbies: Taking pictures, Surfing internet, riding motocycle.

Social Network: 


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Halimi

Name: Muhammad Nurhalimi bin Ahmad Azmil
Age: 20 years old
D.O.B: 18th July 1994
From: Kedah Darul Aman
Hobbies: Reading books, Surfing the internet, 9Gags.

Social Network:

  • Facebook (Muhammad Halimi)
  • Email address (mhalimi94@gmail.com)




???????WhATisPrOTeiN?????????


we know u dont know!!!!!!
 
Proteins are large biological molecule consisting of one or more chains of amino acid residues. Proteins perform a vast array of functions within living organisms, including catalyzing metabolic reaction,  replicating DNA , responding stimuli, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their  genes, and which usually results in folding of the protein into a specific 3D structure that determines its activity.

take a break
 A polypeptide is a single linear polymer chain derived from the condensation of amino acid . The individual amino acid residues are bonded together by peptide bond and adjacent amino acid residues. The sequence of amino acid residues in a protein is defined by the sequence of a gene, which is encoded in the genetic code. In general, the genetic code specifies 20 standard amino acids.

 Proteins are assembled from amino acids using information encoded in genes. Each protein has its own unique amino acid sequence that is specified by the nucleotide sequence of the gene encoding this protein. The genetic code is a set of three-nucleotide sets called codon and each three-nucleotide combination designates an amino acid.
 Genes encoded in DNA are first transcribe into mRNA by proteins such as RNA polymerase. Most organisms then process the pre-mRNA (also known as a primary transcript) using various forms of Post-transciptional modification to form the mature mRNA, which is then used as a template for protein synthesis by the ribosome.
 or
even easier

Most proteins fold into unique 3-dimensional structures. The shape into which a protein naturally folds. four distinct aspects of a protein's structure:

  • 1' structure: the amino acid sequence. A protein is a polymide.
  • 2' structure: regularly repeating local structures stabilized by H bond. The most common examples are the alpha helix, beta sheet and turn. Because secondary structures are local, many regions of different secondary structure can be present in the same protein molecule
  • 3' structure: the overall shape of a single protein molecule; the spatial relationship of the secondary structures to one another. Tertiary structure is generally stabilized by nonlocal interactions, most commonly the formation of a hydrophobic core, but also through salt bridge, hydrogen bonds, disulphide bond. The term "tertiary structure" is often used as synonymous with the term fold. The tertiary structure is what controls the basic function of the protein.
  • quarternary structure : the structure formed by several protein molecules (polypeptide chains), usually called protein subunit in this context, which function as a single protein complex.


now u are protein expert
u right now

end!!!!